Severe Androgenetic Alopecia (male pattern hair loss) has a characteristic pattern of hair loss; it begins with a slight recession at the front hairline and is followed by thinning on the crown of the head. The hair above the ears and at the nape of the neck is unaffected. The hair loss results from a complex chemical reaction when the enzyme 5-alpha-reductase converts the testosterone in the system into DHT or dihydrotestosterone. The hair follicles are genetically predisposed to be over sensitive to the DHT and become smaller and smaller with time, leading to the eventual hair loss.
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